Vutrisiran (sodium)

Vutrisiran sodium is a liver-directed, investigational, small interfering ribonucleic acid (siRNA) agent. Vutrisiran sodium can be used for transthyretin (TTR) -mediated amyloidosis research[1].

Product Specifications

Product Name Alternative

ALN-TTRsc02 (sodium)

UNSPSC

12352208

Target

Small Interfering RNA (siRNA)

Type

Oligonucleotides

Related Pathways

Epigenetics

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/vutrisiran-sodium.html

Purity

97.37

Solubility

10 mM in H2O

Smiles

[Vutrisiran(sodium)]

Molecular Formula

C530H671F9N171Na44O323P43S6

Molecular Weight

16345 (free acid)

References & Citations

[1]Bahru A Habtemariam, et al. Single-Dose Pharmacokinetics and Pharmacodynamics of Transthyretin Targeting N-acetylgalactosamine-Small Interfering Ribonucleic Acid Conjugate, Vutrisiran, in Healthy Subjects. Clin Pharmacol Ther. 2021 Feb;109 (2) :372-382.