Asudemotide
Asudemotide (S-588410) is a peptide of human DEP domain-containing protein 1A. Asudemotide is an immunostimulant. Asudemotide has a sequence of H-Glu-Tyr-Tyr-Glu-Leu-Phe-Val-Asn-Ile-OH. Asudemotide induces a tumor immune response in esophageal cancer. [1].
Product Specifications
CAS Number
[1018833-53-8]
UNSPSC
12352209
Target
PD-1/PD-L1
Type
Peptides
Related Pathways
Immunology/Inflammation
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/asudemotide.html
Solubility
10 mM in DMSO
Smiles
O=C(N[C@@H](CCC(O)=O)C(N[C@@H](CC(C)C)C(N[C@H](C(N[C@@H](C(C)C)C(N[C@@H](CC(N)=O)C(N[C@H](C(O)=O)[C@@H](C)CC)=O)=O)=O)CC1=CC=CC=C1)=O)=O)[C@@H](NC([C@@H](NC([C@@H](N)CCC(O)=O)=O)CC(C=C2)=CC=C2O)=O)CC(C=C3)=CC=C3O
Molecular Formula
C58H80N10O17
Molecular Weight
1189.31
References & Citations
[1]H Daiko, et al.Exploratory open-label clinical study to determine the S-588410 cancer peptide vaccine-induced tumor-infiltrating lymphocytes and changes in the tumor microenvironment in esophageal cancer patients. Cancer Immunol Immunother. 2020, 69, 11.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported
Curated Selection
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