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Asudemotide

Product Specifications

UNSPSC Description

Asudemotide (S-588410) is a peptide of human DEP domain-containing protein 1A. Asudemotide is an immunostimulant. Asudemotide has a sequence of H-Glu-Tyr-Tyr-Glu-Leu-Phe-Val-Asn-Ile-OH. Asudemotide induces a tumor immune response in esophageal cancer. [1].

Target Antigen

PD-1/PD-L1

Type

Peptides

Related Pathways

Immunology/Inflammation

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/asudemotide.html

Solubility

10 mM in DMSO

Smiles

O=C(N[C@@H](CCC(O)=O)C(N[C@@H](CC(C)C)C(N[C@H](C(N[C@@H](C(C)C)C(N[C@@H](CC(N)=O)C(N[C@H](C(O)=O)[C@@H](C)CC)=O)=O)=O)CC1=CC=CC=C1)=O)=O)[C@@H](NC([C@@H](NC([C@@H](N)CCC(O)=O)=O)CC(C=C2)=CC=C2O)=O)CC(C=C3)=CC=C3O

Molecular Weight

1189.31

References & Citations

[1]H Daiko, et al.Exploratory open-label clinical study to determine the S-588410 cancer peptide vaccine-induced tumor-infiltrating lymphocytes and changes in the tumor microenvironment in esophageal cancer patients. Cancer Immunol Immunother. 2020, 69, 11.

Shipping Conditions

Room temperature

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-P1610/Asudemotide-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-P1610/

Clinical Information

No Development Reported

CAS Number

1018833-53-8

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