PF-5212374
PF-5212374 (TRU-015) is a humanized antibody expressed in CHO, targeting CD20/MS4A1. PF-5212374 exhibits potent direct signaling and antibody-dependent cellular cytotoxicity, with complement-mediated cytotoxicity lower than that of Rituximab. PF-5212374 has antitumor activity and can be used in the research of tumors such as lymphoma and inflammatory diseases[1].
Product Specifications
CAS Number
1169717-01-4
Product Name Alternative
TRU-015
UNSPSC
12352203
Target
CD20
Type
Inhibitory Antibodies
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/pf-5212374-tru-015.html
Purity
97.9
Smiles
[PF-5212374]
References & Citations
[1]Hayden-Ledbetter MS, et al. CD20-directed small modular immunopharmaceutical, TRU-015, depletes normal and malignant B cells. Clin Cancer Res. 2009 Apr 15;15 (8) :2739-46.
Shipping Conditions
Dry Ice
Storage Conditions
-80°C
Scientific Category
Inhibitory Antibodies
Clinical Information
Phase 2
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
K4716402 1.0 µg DNA
Hes7 sgRNA CRISPR Lentivector (Mouse) (Target 1)
Sign In for Pricing
View Details 
GTR10382607 96 Well
Monkey Olfactory receptor 4K15 (OR4K15) ELISA kit
Sign In for Pricing
View Details GTR10341496 96 Well
Bovine Adipose Triglyceride Lipase, ATGL ELISA Kit
Sign In for Pricing
View Details 