N- (Amino-PEG2) -N-bis (PEG3-azide)
N- (Amino-PEG2) -N-bis (PEG3-azide) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. N- (Amino-PEG2) -N-bis (PEG3-azide) is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
Product Specifications
CAS Number
[2606952-86-5]
UNSPSC
12352211
Hazard Statement
H302, H315, H319, H335
Target
PROTAC Linkers
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/n-amino-peg2-n-bis-peg3-azide.html
Purity
99.85
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
NCCOCCOCCN(CCOCCOCCOCCN=[N+]=[N-])CCOCCOCCOCCN=[N+]=[N-]
Molecular Formula
C22H46N8O8
Molecular Weight
550.65
Precautions
H302, H315, H319, H335
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light, stored under nitrogen)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
PEG Linkers
Available Sizes
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