α-Amylase-IN-3
Product Specifications
UNSPSC Description
α-Amylase-IN-3 (Compound 4) is a none-competitive type of α-Amylase inhibitor with an IC50 value of 18.04 μM, which also has radical scavenging activities (DPPH and ABTS) with IC50 values of 16.04 μM (DPPH) and 16.99 μM (ABTS), respectively. α-Amylase-IN-3 has good protein–ligand interactions profile against α-Amylase. α-Amylase-IN-3 may have pharmacological activities such as anti-oxidative, anti-inflammatory inhibitory, which is helpful for the development of diabetes and oxidative stress associated disease[1].
Target Antigen
Amylases
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Cancer; Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/α-amylase-in-3.html
Solubility
DMSO : 11.11 mg/mL (ultrasonic;warming;heat to 80°C)
Smiles
O=C(C1=CC2=CC=CC=C2O1)C3=CC=C([N+]([O-])=O)C=C3
Molecular Weight
267.24
References & Citations
[1]Na Li, et al. Design, synthesis and biological evaluation of novel plumbagin derivatives as potent antitumor agents with STAT3 inhibition. Bioorg Chem. 2020 Nov;104:104208.
Shipping Conditions
Room Temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-149008/α-Amylase-IN-3-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-149008/α-Amylase-IN-3-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
93944-58-2
Available Sizes
Curated Selection
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