α-Amylase-IN-3

α-Amylase-IN-3 (Compound 4) is the inhibitor for α-Amylase, AChE and AChE with IC50s of 18.04 μM, 21.04 μM and 22.2 μM, respectively. α-Amylase-IN-3 exhibits antioxidant activity. α-Amylase-IN-3 can be used in research of diabetes and oxidative stress associated disease[1][2].

Product Specifications

CAS Number

[93944-58-2]

UNSPSC

12352005

Target

Amylases; Cholinesterase (ChE)

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease; Neuronal Signaling

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/α-amylase-in-3.html

Purity

99.49

Solubility

DMSO : 11.11 mg/mL (ultrasonic; warming; heat to 80°C)

Smiles

O=C(C1=CC2=CC=CC=C2O1)C3=CC=C([N+]([O-])=O)C=C3

Molecular Formula

C15H9NO4

Molecular Weight

267.24

References & Citations

[1]Na Li, et al. Design, synthesis and biological evaluation of novel plumbagin derivatives as potent antitumor agents with STAT3 inhibition. Bioorg Chem. 2020 Nov;104:104208.|[2]Ali I, et al. Benzofuran Hybrids as Cholinesterase (AChE and BChE) Inhibitors: In Vitro, In Silico, and Kinetic Studies[J]. Russian Journal of Bioorganic Chemistry, 2022, 48 (6) : 1322-1337.