CQ-ER
CQ-ER is a Coumarin (HY-N0709) -Quinazolinone based endoplasmic reticulum (ER) -targeted photosensitizer. CQ-ER can cause ferroptosis, thereby enhancing photodynamic therapy (PDT) [1].
Product Specifications
UNSPSC
12352005
Target
Ferroptosis
Type
Reference compound
Related Pathways
Apoptosis
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/cq-er.html
Smiles
O=C(C(C1=NC2=CC=C(OCC3=CN(CCNS(C4=CC=C(C)C=C4)(=O)=O)N=N3)C=C2C(N1)=O)=C5)OC6=C5C=CC(N(CC)CC)=C6
Molecular Formula
C33H33N7O6S
Molecular Weight
655.72
References & Citations
[1]Xuzi Zhao, et al. Coumarin-Quinazolinone based photosensitizers: Mitochondria and endoplasmic reticulum targeting for enhanced phototherapy via different cell death pathways. Eur J Med Chem. 2024 Oct 19:280:116990.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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