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CQ-ER

Product Specifications

UNSPSC Description

CQ-ER is a Coumarin (HY-N0709)-Quinazolinone based endoplasmic reticulum (ER)-targeted photosensitizer. CQ-ER can cause ferroptosis, thereby enhancing photodynamic therapy (PDT)[1].

Target Antigen

Ferroptosis

Type

Reference compound

Related Pathways

Apoptosis

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/cq-er.html

Smiles

O=C(C(C1=NC2=CC=C(OCC3=CN(CCNS(C4=CC=C(C)C=C4)(=O)=O)N=N3)C=C2C(N1)=O)=C5)OC6=C5C=CC(N(CC)CC)=C6

Molecular Weight

655.72

References & Citations

[1]Xuzi Zhao, et al. Coumarin-Quinazolinone based photosensitizers: Mitochondria and endoplasmic reticulum targeting for enhanced phototherapy via different cell death pathways. Eur J Med Chem. 2024 Oct 19:280:116990.

Shipping Conditions

Room temperature

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-168261/CQ-ER-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-168261/

Clinical Information

No Development Reported

Curated Selection

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