PROTAC DYRK2 degrader 1
Product Specifications
UNSPSC Description
PROTAC DYRK2 degrader 1 (compound CP134) is a PROTAC degrader of DYRK2 (Red: DYRK2 inhibitor(HY-161598), black: linker (HY-42776), Blue: E3 ligase ligand (HY-10984))[1].
Target Antigen
PROTACs
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/protac-dyrk2-degrader-1.html
Smiles
O=C(NCCOCCOCCOCCNC1=CC=CC(C(N2C(CC3)C(NC3=O)=O)=O)=C1C2=O)CN4C/C(C(/C(C4)=C/C5=CC=CC=C5Br)=O)=C\C6=CC=CC=C6Br
Molecular Weight
921.63
References & Citations
[1]Jian Chen, et al.Discovery of the First Potent DYRK2 Proteolysis Targeting Chimera Degraders. ACS Med. Chem. Lett. 2024, 15, 5, 659–666.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-161597/PROTAC-DYRK2-degrader-1-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-161597/
Clinical Information
No Development Reported
Curated Selection
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