SRPIN340
SRPIN340 is an ATP-competitive serine-arginine-rich protein kinase (SRPK) inhibitor, with a Ki of 0.89 μM for SRPK1.
Product Specifications
CAS Number
218156-96-8
Product Name Alternative
SRPK inhibitor
UNSPSC
12352005
Hazard Statement
H302
Target
SRPK; Virus Protease
Type
Reference compound
Related Pathways
Anti-infection; Cell Cycle/DNA Damage
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/SRPIN340.html
Concentration
10mM
Purity
99.62
Solubility
DMSO : ≥ 42 mg/mL
Smiles
O=C(NC1=CC(C(F)(F)F)=CC=C1N2CCCCC2)C3=CC=NC=C3
Molecular Formula
C18H18F3N3O
Molecular Weight
349.35
Precautions
H302
References & Citations
[1]Fukuhara T, et al. Utilization of host SR protein kinases and RNA-splicing machinery during viral replication. Proc Natl Acad Sci U S A. 2006 Jul 25;103 (30) :11329-33.|[2]Siqueira RP, et al. Potential Antileukemia Effect and Structural Analyses of SRPK Inhibition by N- (2- (Piperidin-1-yl) -5- (Trifluoromethyl) Phenyl) Isonicotinamide (SRPIN340) . PLoS One. 2015 Aug 5;10 (8) :e0134882.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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