Glycycoumarin (Standard)
Product Specifications
UNSPSC Description
Glycycoumarin (Standard) is the analytical standard of Glycycoumarin. This product is intended for research and analytical applications. Glycycoumarin is a potent antispasmodic agent. Glycycoumarin is a major bioactive coumarin of licorice and exhibits antispasmodic activity. Glycycoumarin also has hepatoprotective effect. Glycycoumarin can be used for the research of abdominal pain and liver diseases[1][2].
Target Antigen
AMPK; Keap1-Nrf2
Type
Reference compound
Related Pathways
Epigenetics;NF-κB;PI3K/Akt/mTOR
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/glycycoumarin-standard.html
Smiles
O=C1C(C2=CC=C(O)C=C2O)=CC3=C(OC)C(C/C=C(C)\C)=C(O)C=C3O1
Molecular Weight
368.38
References & Citations
[1]Yuji Sato, et al. Glycycoumarin from Glycyrrhizae Radix acts as a potent antispasmodic through inhibition of phosphodiesterase 3. J Ethnopharmacol. 2006 May 24;105(3):409-14. |[2]Enxiang Zhang, et al. Protective effects of glycycoumarin on liver diseases. Phytother Res. 2020 Jun;34(6):1191-1197.|[3]Zhang E, et al. Glycycoumarin Sensitizes Liver Cancer Cells to ABT-737 by Targeting De Novo Lipogenesis and TOPK-Survivin Axis. Nutrients. 2018 Mar 15;10(3):353.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-N4113R/Glycycoumarin-Standard-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-N4113R/
CAS Number
94805-82-0
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