Glycycoumarin (Standard)

Glycycoumarin (Standard) is the analytical standard of Glycycoumarin. This product is intended for research and analytical applications. Glycycoumarin is a potent antispasmodic agent. Glycycoumarin is a major bioactive coumarin of licorice and exhibits antispasmodic activity. Glycycoumarin also has hepatoprotective effect. Glycycoumarin can be used for the research of abdominal pain and liver diseases[1][2].

Product Specifications

CAS Number

[94805-82-0]

UNSPSC

12352005

Target

AMPK; Keap1-Nrf2; Reference Standards

Type

Reference compound

Related Pathways

Epigenetics; NF-κB; Others; PI3K/Akt/mTOR

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/glycycoumarin-standard.html

Smiles

O=C1C(C2=CC=C(O)C=C2O)=CC3=C(OC)C(C/C=C(C)\C)=C(O)C=C3O1

Molecular Formula

C21H20O6

Molecular Weight

368.38

References & Citations

[1]Yuji Sato, et al. Glycycoumarin from Glycyrrhizae Radix acts as a potent antispasmodic through inhibition of phosphodiesterase 3. J Ethnopharmacol. 2006 May 24;105 (3) :409-14. |[2]Enxiang Zhang, et al. Protective effects of glycycoumarin on liver diseases. Phytother Res. 2020 Jun;34 (6) :1191-1197.|[3]Zhang E, et al. Glycycoumarin Sensitizes Liver Cancer Cells to ABT-737 by Targeting De Novo Lipogenesis and TOPK-Survivin Axis. Nutrients. 2018 Mar 15;10 (3) :353.