AS 1411 (sodium)
AS1411 sodium is a quadruplex-forming oligonucleotide aptamer that targets nucleolin. It has anti-tumor activity.
Product Specifications
Product Name Alternative
AGRO-100 (sodium)
UNSPSC
12352208
Target
DNA/RNA Synthesis
Type
Oligonucleotides
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/as-1411-sodium.html
Purity
99.52
Solubility
H2O : ≥ 100 mg/mL
Smiles
[AS1411(sodium)]
Molecular Weight
8272.31
References & Citations
[1]Teng Y, et al. AS1411 alters the localization of a complex containing protein arginine methyltransferase 5 and nucleolin. Cancer Res. 2007;67 (21) :10491-10500. |[2]Soundararajan S, et al. The nucleolin targeting aptamer AS1411 destabilizes Bcl-2 messenger RNA in human breast cancer cells. Cancer Res. 2008;68 (7) :2358-2365.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture)
Scientific Category
Oligonucleotides
Clinical Information
Phase 2
Citation 01
Phytomedicine. 2025 Jun 2:144:156932.|Int J Pharm X. 2025 Jun.
Available Sizes
Curated Selection
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