Pantethine-15N2
Product Specifications
UNSPSC Description
Pantethine-15N2 is the 15N2 labeled Pantethine. Pantethine is an orally active lipid-lowering agent. Pantethine has anti-tumor, anti-inflammatory and anti-SARS-COV virus activities. Pantethine is also a neuroprotective agent. Pantethine can be used in the study of Alzheimer's disease, Parkinson's disease, major depression, systemic sclerosis and pantothenate kinase-related neurodegeneration[1][2][3][4][5][6].
Target Antigen
Isotope-Labeled Compounds
Type
Isotope-Labeled Compounds
Related Pathways
Others
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Cancer; Endocrinology; Metabolic Disease; Inflammation/Immunology; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/pantethine-15n2.html
Solubility
10 mM in DMSO
Smiles
O=C([15NH]CCSSCC[15NH]C(CCNC([C@H](O)C(C)(C)CO)=O)=O)CCNC([C@H](O)C(C)(C)CO)=O
Molecular Weight
556.71
References & Citations
[1]Bocos C, et al. Pantethine stimulates lipolysis in adipose tissue and inhibits cholesterol and fatty acid synthesis in liver and intestinal mucosa in the normolipidemic rat. Environ Toxicol Pharmacol. 1998 Aug 4;6(1):59-66.|[2]Abou-Hamdan M, et al. Potential antiviral effects of pantethine against SARS-CoV-2. Sci Rep. 2023 Feb 8;13(1):2237.|[3]Penet MF, et al. Effect of Pantethine on Ovarian Tumor Progression and Choline Metabolism. Front Oncol. 2016 Nov 16;6:244.|[4]Tóth F, et al. Natural Molecules and Neuroprotection: Kynurenic Acid, Pantethine and α-Lipoic Acid. Int J Mol Sci. 2021 Jan 2;22(1):403.|[5]Kavian N, et al. Pantethine Prevents Murine Systemic Sclerosis Through the Inhibition of Microparticle Shedding. Arthritis Rheumatol. 2015 Jul;67(7):1881-90. |[6]Brunetti D, et al. Pantethine treatment is effective in recovering the disease phenotype induced by ketogenic diet in a pantothenate kinase-associated neurodegeneration mouse model. Brain. 2014 Jan;137(Pt 1):57-68.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-B1028S/Pantethine-15N2-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-B1028S/
Clinical Information
No Development Reported
Curated Selection
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