4- (2-Bromoacetyl) benzonitrile

4- (2-Bromoacetyl) benzonitrile (4-Cyanophenacyl bromide) can be used to the synthesis of STA-5312. STA-5312 is a potent and orally active microtubule inhibitor[1][2].

Product Specifications

CAS Number

[20099-89-2]

Product Name Alternative

4-Cyanophenacyl bromide

UNSPSC

12352005

Hazard Statement

H302+H312+H332, H314

Target

Biochemical Assay Reagents

Type

Reference compound

Related Pathways

Others

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/4-2-bromoacetyl-benzonitrile.html

Purity

99.78

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

N#CC1=CC=C(C(CBr)=O)C=C1

Molecular Formula

C9H6BrNO

Molecular Weight

224.06

Precautions

H302+H312+H332, H314

References & Citations

[1]Hao Li, et al. Development of a Practical Synthesis of STA-5312, a Novel Indolizine Oxalylamide Microtubule Inhibitor. Org. Process Res. Dev. 2007, 11, 2, 246–250|[2]Keizo Koya, et al. STA-5312, a novel tubulin inhibitor, demonstrates the anti-cancer activity against chemotherapy-resistant cancers. Cancer Res, Volume 45, 2004.