EGFR-IN-121
EGFR-IN-121 (compound 15) is a EGFR and VEGFR-2 dual inhibitor with IC50s of 84 and 3.5 nM, respectively[1].
Product Specifications
CAS Number
418799-16-3
UNSPSC
12352005
Target
EGFR
Type
Reference compound
Related Pathways
JAK/STAT Signaling; Protein Tyrosine Kinase/RTK
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/egfr-in-121.html
Smiles
O=C(C1=C(C)NC(NC1C2=CC=C(OCC3=CC=CC=C3)C(OC)=C2)=O)OC(C)C
Molecular Formula
C23H26N2O5
Molecular Weight
410.46
References & Citations
[1]Al-Wahaibi L H, et al. Design and Synthesis of New Dihydropyrimidine Derivatives with a Cytotoxic Effect as Dual EGFR/VEGFR-2 Inhibitors[J]. ACS Omega, 2024.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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