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ACT-678689

ACT-678689 (Compound Example 1.53.4) is a tryptophan hydroxylase (TPH) inhibitor with an IC50 of 8 nM[1].

Product Specifications

CAS Number

[1783256-96-1]

UNSPSC

12352005

Target

Tryptophan Hydroxylase

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/act-678689.html

Purity

99.91

Solubility

DMSO : ≥ 100 mg/mL

Smiles

CS(=O)(NC1=NC(Cl)=C(OCC(N2CCC3=C(N4C(SC(C)=N4)=N3)[C@@H]2C5=CC=C(C)C=C5F)=O)C=C1)=O

Molecular Formula

C23H22ClFN6O4S2

Molecular Weight

565.04

References & Citations

[1]Daniel Bur, et al. Tricyclic piperidine compounds. WO2015075023A1.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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