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Ac-Tyr-Val-Lys-Asp-aldehyde

Ac-Tyr-Val-Lys-Asp-aldehyde is a reversible caspase-1 inhibitor. Ac-Tyr-Val-Lys-Asp-aldehyde increases GATA1 levels by inhibiting caspase-1 and promotes erythroid differentiation. can be used for disease research including anemia-associated to chronic diseases, chemotherapy-induced anemia and Diamond-Blackfan anemia[1].

Product Specifications

CAS Number

[147821-01-0]

UNSPSC

12352209

Target

Caspase

Type

Peptides

Related Pathways

Apoptosis

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/ac-tyr-val-lys-asp-aldehyde.html

Purity

99.89

Solubility

DMSO : 62.5 mg/mL (ultrasonic)

Smiles

OC(C=C1)=CC=C1C[C@H](NC(C)=O)C(N[C@@H](C(C)C)C(N[C@@H](CCCCN)C(N[C@H](C=O)CC(O)=O)=O)=O)=O

Molecular Formula

C26H39N5O8

Molecular Weight

549.62

References & Citations

[1]Mulero Mendez, et al. Caspase 1 inhibitors for the treatment of anemia: Spain, ES2769975[P]. 2020-06-29.

Shipping Conditions

Blue Ice

Storage Conditions

-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)

Scientific Category

Peptides

Clinical Information

No Development Reported

Isoform

Caspase 1

Available Sizes

Curated Selection

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