Taspine

Taspine is a natural product with anti-inflammatory activity. Taspine suppresses P2X4 receptor activity via PI3K inhibition. Taspine inhibits pro-inflammatory signalling via inhibition of P2X4 receptors in macrophage[1].

Product Specifications

CAS Number

[602-07-3]

UNSPSC

12352005

Target

P2X Receptor

Type

Natural Products

Related Pathways

Membrane Transporter/Ion Channel

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/taspine.html

Purity

98.0

Solubility

10 mM in DMSO

Smiles

O=C1C2=CC=C(OC)C(O3)=C2C4=C(C3=O)C(CCN(C)C)=CC(OC)=C4O1

Molecular Formula

C20H19NO6

Molecular Weight

369.37

References & Citations

[1]Izzuddin Bin Nadzirin, et al. Taspine is a natural product that suppresses P2X4 receptor activity via phosphoinositide 3-kinase inhibition. Br J Pharmacol. 2021 Dec;178 (24) :4859-4872.