MethylCBI-azaindole-benzamide-MOM-Boc-ethylenediamine-D
MethylCBI-azaindole-benzamide-MOM-Boc-ethylenediamine-D is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) [1].
Product Specifications
CAS Number
[2222445-87-4]
UNSPSC
12352203
Hazard Statement
H302, H315, H319, H335
Target
ADC Linker
Type
ADC Related
Related Pathways
Antibody-drug Conjugate/ADC Related
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/methylcbi-azaindole-benzamide-mom-boc-ethylenediamine-d.html
Purity
99.65
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
ClC[C@H]1C2=C(C=C(C3=CC=CC(C)=C32)OC(N(CCOCCO)CCN(C)C(OC(C)(C)C)=O)=O)N(C1)C(C4=CN(C=C(C=C5)NC(C6=CC=C(C=C6)OCOC)=O)C5=N4)=O
Molecular Formula
C44H51ClN6O10
Molecular Weight
859.36
Precautions
H302, H315, H319, H335
References & Citations
[1]Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017;16 (5) :315-337.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
ADC Related
Clinical Information
No Development Reported
Isoform
Cleavable Linker
Available Sizes
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