3'-O-Methylguanosine

3'-O-Methylguanosine is a methylated nucleoside analog and RNA chain terminator. 3'-O-Methylguanosine can inhibit the synthesis of early vaccinia virus-specific RNA[1].

Product Specifications

CAS Number

[10300-27-3]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

DNA/RNA Synthesis; Endogenous Metabolite; Nucleoside Antimetabolite/Analog; Orthopoxvirus

Type

Reference compound

Related Pathways

Anti-infection; Cell Cycle/DNA Damage; Metabolic Enzyme/Protease

Applications

COVID-19-anti-virus

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/3-o-methylguanosine.html

Purity

99.98

Solubility

DMSO : 25 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

O[C@@H]1[C@H](OC)[C@@H](CO)O[C@H]1N2C=NC3=C2NC(N)=NC3=O

Molecular Formula

C11H15N5O5

Molecular Weight

297.27

Precautions

H302, H315, H319, H335

References & Citations

[1]B B Goswami, et al. Inhibition of vaccinia virus growth and virus-specific RNA synthesis by 3'-O-methyl adenosine and 3'-O-methyl guanosine. J Virol. 1983 Mar;45 (3) :1164-7.