DAO-IN-1
DAO-IN-1 is a potent inhibitor of D-amino acid oxidase (DAO) with an IC50 value of 269 nM. DAO is an enzyme responsible for D-serine metabolism, D-serine is a co-agonist of NMDA receptors[1].
Product Specifications
CAS Number
[51856-25-8]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Xanthine Oxidase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/dao-in-1.html
Purity
97.46
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(C1=CC(C=CS2)=C2N1)O
Molecular Formula
C7H5NO2S
Molecular Weight
167.19
Precautions
H302, H315, H319, H335
References & Citations
[1]Sparey T, et al. The discovery of fused pyrrole carboxylic acids as novel, potent D-amino acid oxidase (DAO) inhibitors. Bioorg Med Chem Lett. 2008 Jun 1;18 (11) :3386-91.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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