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DAO-IN-1

DAO-IN-1 is a potent inhibitor of D-amino acid oxidase (DAO) with an IC50 value of 269 nM. DAO is an enzyme responsible for D-serine metabolism, D-serine is a co-agonist of NMDA receptors[1].

Product Specifications

CAS Number

51856-25-8

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Xanthine Oxidase

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/dao-in-1.html

Purity

97.46

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C(C1=CC(C=CS2)=C2N1)O

Molecular Formula

C7H5NO2S

Molecular Weight

167.19

Precautions

H302, H315, H319, H335

References & Citations

[1]Sparey T, et al. The discovery of fused pyrrole carboxylic acids as novel, potent D-amino acid oxidase (DAO) inhibitors. Bioorg Med Chem Lett. 2008 Jun 1;18 (11) :3386-91.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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