LPA5 antagonist 2
Product Specifications
UNSPSC Description
LPA5 antagonist 2 (compound 65) is a high aqueous solubility LPA5 (lysophosphatidic acid receptor 5) antagonist. LPA5 antagonist 2 significantly attenuates nociceptive hypersensitivity and it can be used for the research of inflammatory and neuropathic pains[1].
Target Antigen
LPL Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/lpa5-antagonist-2.html
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C1N(C2=CC=C3C(C(C)=CS3)=C2)C=C(C(N4CCC(F)CC4)=O)C5=C1C=C(OC)C(OC)=C5
Molecular Weight
480.55
References & Citations
[1]Zhang DH, et al. Isoquinolone derivatives as lysophosphatidic acid receptor 5 (LPA5) antagonists: Investigation of structure-activity relationships, ADME properties and analgesic effects. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY. 2022.
Shipping Conditions
Blue Ice
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-151392/LPA5-antagonist-2-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-151392/LPA5-antagonist-2-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
2839471-44-0
Available Sizes
Curated Selection
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