Anti-Mouse IL-10 Antibody (JES5-2A5)

Anti-Mouse IL-10 Antibody (JES5-2A5) is an anti-mouse IL-10 IgG1 monoclonal antibody. Anti-Mouse IL-10 Antibody (JES5-2A5) restores the anti-tumor activity of IL-6 by blocking the IL-10/SOCS3 axis. Anti-Mouse IL-10 Antibody (JES5-2A5) can reverse microcirculation and cognitive deficits. Anti-Mouse IL-10 Antibody (JES5-2A5) can be used for researches on cancer and metabolic disease such as osteosarcoma and type 1 diabetes mellitus (T1DM) [1][2][3].

Product Specifications

CAS Number

[9007-83-4]

UNSPSC

12352203

Target

Interleukin Related

Type

Inhibitory Antibodies

Related Pathways

Immunology/Inflammation

Applications

COVID-19-immunoregulation

Field of Research

Cancer; Metabolic Disease; Inflammation/Immunology; Neurological Disease

Assay Protocol

https://www.medchemexpress.com/anti-mouse-il-10-antibody-jes5-2a5.html

Purity

95.0

Solubility

10 mM in DMSO

Smiles

[Anti-MouseIL-10Antibody(JES5-2A5)]

Molecular Weight

(150 kDa)

References & Citations

[1]Zahoor I, et al. Maresin-1 promotes neuroprotection and modulates metabolic and inflammatory responses in disease-associated cell types in preclinical models of multiple sclerosis. J Biol Chem. 2025 Mar;301 (3) :108226.|[2]Sharma S, et al. A pathogenic role for IL-10 signalling in capillary stalling and cognitive impairment in type 1 diabetes. Nat Metab. 2024 Nov;6 (11) :2082-2099.|[3]Nastasi N, et al. Blockade of IL-10 Signaling Ensures Mifamurtide Efficacy in Metastatic Osteosarcoma. Cancers (Basel) . 2023 Sep 27;15 (19) :4744.