What is the catalog number for AdipoRon?

The catalog number for AdipoRon is HY-15848.

What sizes are available for AdipoRon?

AdipoRon is available in the following size(s): 5 mg, 10 mg, 10 mM - 1 mL, 25 mg, 50 mg, 100 mg, 200 mg, 1 g.

How many pack sizes does AdipoRon come in?

AdipoRon is available in 8 different pack sizes.

Is AdipoRon in stock?

AdipoRon is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures AdipoRon?

AdipoRon is manufactured by QuantiMol.

What is the estimated delivery time for AdipoRon?

Estimated delivery time for AdipoRon is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for AdipoRon?

The safety data sheet for AdipoRon is available here: http://file.medchemexpress.com/batch_PDF/HY-15848/AdipoRon-SDS-MedChemExpress.pdf.

AdipoRon

AdipoRon is an orally active adiponectin receptor (AdipoR) agonist, binding to AdipoR1 and AdipoR2 with Kds of 1.8 and 3.1 μM, respectively.

Product Specifications

CAS Number

924416-43-3

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Adiponectin Receptor

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/AdipoRon.html

Purity

99.88

Solubility

DMSO : 62.5 mg/mL (ultrasonic) |H2O : < 0.1 mg/mL

Smiles

O=C(NC1CCN(CC2=CC=CC=C2)CC1)COC3=CC=C(C(C4=CC=CC=C4)=O)C=C3

Molecular Formula

C27H28N2O3

Molecular Weight

428.53

Precautions

H302, H315, H319, H335

References & Citations

[1]Okada-Iwabu M, et al. A small-molecule AdipoR agonist for type 2 diabetes and short life in obesity. Nature. 2013 Nov 28;503 (7477) :493-9.|[2]Wang Y, et al. Hepatoprotective effects of AdipoRon against d-galactosamine-induced liver injury in mice. Eur J Pharm Sci. 2016 Aug 9;93:123-131.|[3]Zhang Y, et al. AdipoRon, the first orally active adiponectin receptor activator, attenuates postischemic myocardial apoptosis through both AMPK-mediated and AMPK-independent signalings. Am J Physiol Endocrinol Metab. 2015 Aug 1;309 (3) :E275-82.|[4]Hong K, et al. Adiponectin Receptor Agonist, AdipoRon, Causes Vasorelaxation Predominantly Via a Direct Smooth Muscle Action. Microcirculation. 2016 Apr;23 (3) :207-20.