Bizine di (hydrochloride)
Bizine dihydrochloride, a Phenelzine analogue, is a potent and selective LSD1 inhibitor, with a b>Ki of 59 nM. Bizine dihydrochloride can modulate bulk histone methylation in cancer cells. Bizine dihydrochloride shows neuroprotective effects[1].
Product Specifications
CAS Number
1808112-57-3
UNSPSC
12352005
Target
Histone Demethylase
Type
Reference compound
Related Pathways
Epigenetics
Field of Research
Cancer; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/bizine-di-hydrochloride.html
Purity
99.90
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(NC1=CC=C(CCNN)C=C1)CCCC2=CC=CC=C2.Cl.Cl
Molecular Formula
C18H25Cl2N3O
Molecular Weight
370.32
References & Citations
[1]Prusevich P, et, al. A selective phenelzine analogue inhibitor of histone demethylase LSD1. ACS Chem Biol. 2014 Jun 20;9 (6) :1284-93.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
Histone H1 (AE-4), CF640R conjugate, 0.1mg/mL
MUC18 / Mucin 18 / CD146 (OJ79c), CF488A conjugate, 0.1mg/mL
Insulin (2D11-H5), CF488A conjugate, 0.1mg/mL
