Bizine di (hydrochloride)
Bizine dihydrochloride, a Phenelzine analogue, is a potent and selective LSD1 inhibitor, with a b>Ki of 59 nM. Bizine dihydrochloride can modulate bulk histone methylation in cancer cells. Bizine dihydrochloride shows neuroprotective effects[1].
Product Specifications
CAS Number
1808112-57-3
UNSPSC
12352005
Target
Histone Demethylase
Type
Reference compound
Related Pathways
Epigenetics
Field of Research
Cancer; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/bizine-di-hydrochloride.html
Purity
99.90
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(NC1=CC=C(CCNN)C=C1)CCCC2=CC=CC=C2.Cl.Cl
Molecular Formula
C18H25Cl2N3O
Molecular Weight
370.32
References & Citations
[1]Prusevich P, et, al. A selective phenelzine analogue inhibitor of histone demethylase LSD1. ACS Chem Biol. 2014 Jun 20;9 (6) :1284-93.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
Insulin (2D11-H5), CF640R conjugate, 0.1mg/mL
Cytokeratin 17 (E3), CF594 conjugate, 0.1mg/mL
CD50 / ICAM3 (CG106), CF488A conjugate, 0.1mg/mL
