Mianserin (hydrochloride)

Mianserin hydrochloride (Org GB 94) is a H1 receptor inverse agonist and is a psychoactive agent of the tetracyclic antidepressant.

Product Specifications

CAS Number

[21535-47-7]

Product Name Alternative

Org GB 94

UNSPSC

12352005

Hazard Statement

H302

Target

Histamine Receptor

Type

Natural Products

Related Pathways

GPCR/G Protein; Immunology/Inflammation; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease; Endocrinology

Assay Protocol

https://www.medchemexpress.com/mianserin-hydrochloride.html

Purity

99.95

Solubility

DMSO : 50 mg/mL (ultrasonic) |H2O : 25 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

CN(CC1)CC2N1C3=CC=CC=C3CC4=CC=CC=C24.Cl

Molecular Formula

C18H21ClN2

Molecular Weight

300.83

Precautions

H302

References & Citations

[1]Olianas MC, et al. The atypical antidepressant mianserin exhibits agonist activity at κ-opioid receptors. Br J Pharmacol. 2012 Nov;167 (6) :1329-41.|[2]Roeder T. High-affinity antagonists of the locust neuronal octopamine receptor. Eur J Pharmacol. 1990 Nov 27;191 (2) :221-4.