Mianserin (hydrochloride)
Mianserin hydrochloride (Org GB 94) is a H1 receptor inverse agonist and is a psychoactive agent of the tetracyclic antidepressant.
Product Specifications
CAS Number
[21535-47-7]
Product Name Alternative
Org GB 94
UNSPSC
12352005
Hazard Statement
H302
Target
Histamine Receptor
Type
Natural Products
Related Pathways
GPCR/G Protein; Immunology/Inflammation; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease; Endocrinology
Assay Protocol
https://www.medchemexpress.com/mianserin-hydrochloride.html
Purity
99.95
Solubility
DMSO : 50 mg/mL (ultrasonic) |H2O : 25 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
CN(CC1)CC2N1C3=CC=CC=C3CC4=CC=CC=C24.Cl
Molecular Formula
C18H21ClN2
Molecular Weight
300.83
Precautions
H302
References & Citations
[1]Olianas MC, et al. The atypical antidepressant mianserin exhibits agonist activity at κ-opioid receptors. Br J Pharmacol. 2012 Nov;167 (6) :1329-41.|[2]Roeder T. High-affinity antagonists of the locust neuronal octopamine receptor. Eur J Pharmacol. 1990 Nov 27;191 (2) :221-4.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Natural Products
Clinical Information
Launched
Isoform
H1 Receptor
Available Sizes
Curated Selection
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