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Biotinylated leptomycin B

Biotinylated leptomycin B is a compound used to quantify nuclear export protein 1 (XPO1) occupancy and is used to study the interaction of SINE compounds with XPO1 and the response of cancer cells to related compounds.

Product Specifications

UNSPSC

12352005

Target

CRM1

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/biotinylated-leptomycin-b.html

Purity

99.32

Solubility

DMSO : ≥ 300 mg/mL

Smiles

O=C(NCCCCCCNC(CCCC[C@@H]1SC[C@]([C@]1([H])N2)([H])NC2=O)=O)/C=C(C)/C[C@H](C)[C@@H](O)[C@H](C)C([C@H](C)/C=C(C)/C=C/C[C@@H](C)/C=C(CC)\C=C\[C@H]3[C@@H](C)C=CC(O3)=O)=O

Molecular Formula

C49H76N4O7S

Molecular Weight

865.22

References & Citations

[1]A method for quantification of exportin-1 (XPO1) occupancy by Selective Inhibitor of Nuclear Export (SINE) compounds

Shipping Conditions

Blue Ice

Storage Conditions

-20°C (Powder, protect from light, stored under nitrogen)

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-164710/Biotinylated-leptomycin-B-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-164710/Biotinylated-leptomycin-B-SDS-MedChemExpress.pdf

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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