Lucidin primeveroside

Lucidin primeveroside (Lucidin 3-O-β-primeveroside) is an anthraquinone derivative present in madder root, which has been used as a coloring agent and food additive. Lucidin primeveroside can be metabolically converted to genotoxic compound Lucidin, which subsequently forms lucidin-specific DNA adducts[1][2].

Product Specifications

CAS Number

[29706-59-0]

Product Name Alternative

Lucidin 3-O-β-primeveroside

UNSPSC

12352005

Hazard Statement

H302, H351

Target

Others

Type

Natural Products

Related Pathways

Others

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/lucidin-primeveroside.html

Purity

99.95

Solubility

H2O : 5 mg/mL (ultrasonic; warming)

Smiles

O=C(C1=CC=CC=C21)C(C(C2=O)=C3O)=CC(O[C@@H]([C@@H]([C@H]4O)O)O[C@@H]([C@H]4O)CO[C@H](OC[C@H]5O)[C@@H]([C@H]5O)O)=C3CO

Molecular Formula

C26H28O14

Molecular Weight

564.49

Precautions

H302, H351

References & Citations

[1]Yockey OP, et, al. Mechanism of Error-Free DNA Replication Past Lucidin-Derived DNA Damage by Human DNA Polymerase κ. Chem Res Toxicol. 2017 Nov 20;30 (11) :2023-2032.|[2]Ishii Y, et, al. Effects of inhibition of hepatic sulfotransferase activity on renal genotoxicity induced by lucidin-3-O-primeveroside. J Appl Toxicol. 2019 Apr;39 (4) :650-657.