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MUSK rabbit pAb

This gene encodes a muscle-specific tyrosine kinase receptor. The encoded protein may play a role in clustering of the acetylcholine receptor in the postsynaptic neuromuscular junction. Mutations in this gene have been associated with congenital myasthenic syndrome. Alternatively spliced transcript variants have been described. [provided by RefSeq, Oct 2009],

Product Specifications

Background

This gene encodes a muscle-specific tyrosine kinase receptor. The encoded protein may play a role in clustering of the acetylcholine receptor in the postsynaptic neuromuscular junction. Mutations in this gene have been associated with congenital myasthenic syndrome. Alternatively spliced transcript variants have been described.[provided by RefSeq, Oct 2009]

Synonyms

Muscle, skeletal receptor tyrosine-protein kinase (EC 2.7.10.1;Muscle-specific tyrosine-protein kinase receptor;MuSK;Muscle-specific kinase receptor)

Gene ID

4593

UniProt

O15146

Cellular Locus

Cell junction, synapse, postsynaptic cell membrane ; Single-pass type I membrane protein. Colocalizes with acetylcholine receptors (AChR) to the postsynaptic cell membrane of the neuromuscular junction..

Host

Rabbit

Species Reactivity

Human,Rat,Mouse,

Reactivity

Human; Rat; Mouse

Immunogen

Synthesized peptide derived from human MUSK

Clonality

Polyclonal

Isotype

IgG

Source

Rabbit

Applications

WB, IHC

Validated Applications

WB,IHC

Stability

-20°C/1 year

Concentration

1 mg/mL

Dilution

WB 1:500-2000; IHC-p 1:50-300

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES20265-1.pdf

Subcellular Location

Cell junction, synapse, postsynaptic cell membrane ; Single-pass type I membrane protein . Colocalizes with acetylcholine receptors (AChR) to the postsynaptic cell membrane of the neuromuscular junction. .

Other Product Names

Muscle, skeletal receptor tyrosine-protein kinase (EC 2.7.10.1; Muscle-specific tyrosine-protein kinase receptor; MuSK; Muscle-specific kinase receptor)

Gene ID (Human)

4593

SwissProt (Human)

O15146

Available Sizes

Curated Selection

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