MUSK rabbit pAb

This gene encodes a muscle-specific tyrosine kinase receptor. The encoded protein may play a role in clustering of the acetylcholine receptor in the postsynaptic neuromuscular junction. Mutations in this gene have been associated with congenital myasthenic syndrome. Alternatively spliced transcript variants have been described. [provided by RefSeq, Oct 2009],

Product Specifications

Background

UniProt

O15146

Swiss Prot

O15146

Reactivity

Human; Rat; Mouse

Immunogen

Synthesized peptide derived from human MUSK

Clonality

Polyclonal

Source

Rabbit

Applications

WB; IHC

Concentration

1 mg/ml

Dilution

WB 1:500-2000; IHC-p 1:50-300

Storage Conditions

-20°C/1 year

Fragment

IgG

Subcellular Location

Cell junction, synapse, postsynaptic cell membrane ; Single-pass type I membrane protein . Colocalizes with acetylcholine receptors (AChR) to the postsynaptic cell membrane of the neuromuscular junction. .

Other Product Names

Muscle, skeletal receptor tyrosine-protein kinase (EC 2.7.10.1; Muscle-specific tyrosine-protein kinase receptor; MuSK; Muscle-specific kinase receptor)