MAChR-IN-1 (hydrochloride)

MAChR-IN-1 hydrochloride is a potent muscarinic cholinergic receptor (mAChR) antagonist, with an IC50 of 17 nM[1].

Product Specifications

CAS Number

[119391-73-0]

UNSPSC

12352005

Target

MAChR

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/machr-in-1-hydrochloride.html

Purity

99.64

Solubility

DMSO : 65 mg/mL (ultrasonic) |H2O : 1 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

O=C(C(C1CCN(CC2=CC=C(I)C=C2)CC1)(C3=CC=CC=C3)CC4)NC4=O.[H]Cl

Molecular Formula

C23H26ClIN2O2

Molecular Weight

524.82

References & Citations

[1]Wilson AA, et al. Synthesis and biological evaluation of [125I]- and [123I]-4-iododexetimide, a potent muscarinic cholinergic receptor antagonist. J Med Chem. 1989 May;32 (5) :1057-62.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, sealed storage, away from moisture and light)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

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