MAChR-IN-1 (hydrochloride)
MAChR-IN-1 hydrochloride is a potent muscarinic cholinergic receptor (mAChR) antagonist, with an IC50 of 17 nM[1].
Product Specifications
CAS Number
[119391-73-0]
UNSPSC
12352005
Target
MAChR
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/machr-in-1-hydrochloride.html
Purity
99.64
Solubility
DMSO : 65 mg/mL (ultrasonic) |H2O : 1 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C(C(C1CCN(CC2=CC=C(I)C=C2)CC1)(C3=CC=CC=C3)CC4)NC4=O.[H]Cl
Molecular Formula
C23H26ClIN2O2
Molecular Weight
524.82
References & Citations
[1]Wilson AA, et al. Synthesis and biological evaluation of [125I]- and [123I]-4-iododexetimide, a potent muscarinic cholinergic receptor antagonist. J Med Chem. 1989 May;32 (5) :1057-62.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
More Discoveries
Explore Other Products
Browse additional items from our catalog
K1497304 1.0 µg DNA
OR2M7 sgRNA CRISPR Lentivector (Human) (Target 3)
Sign In for Pricing
View Details GTR15216041 1 Vial
Lentiviral mouse Mrpl11 shRNA (UAS) - Lentiviral mouse Mrpl11 shRNA (UAS) (25)
Sign In for Pricing
View Details 