MAChR-IN-1 (hydrochloride)
MAChR-IN-1 hydrochloride is a potent muscarinic cholinergic receptor (mAChR) antagonist, with an IC50 of 17 nM[1].
Product Specifications
CAS Number
[119391-73-0]
UNSPSC
12352005
Target
MAChR
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/machr-in-1-hydrochloride.html
Purity
99.64
Solubility
DMSO : 65 mg/mL (ultrasonic) |H2O : 1 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C(C(C1CCN(CC2=CC=C(I)C=C2)CC1)(C3=CC=CC=C3)CC4)NC4=O.[H]Cl
Molecular Formula
C23H26ClIN2O2
Molecular Weight
524.82
References & Citations
[1]Wilson AA, et al. Synthesis and biological evaluation of [125I]- and [123I]-4-iododexetimide, a potent muscarinic cholinergic receptor antagonist. J Med Chem. 1989 May;32 (5) :1057-62.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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