Woodtide

Woodtide is a substrate for the DYRK (DYRK) family of kinases whose sequence is based on that around the DYRK phosphorylation site in FKHR[1][2].

Product Specifications

CAS Number

[634592-23-7]

UNSPSC

12352209

Target

DYRK

Type

Peptides

Related Pathways

Protein Tyrosine Kinase/RTK

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/woodtide.html

Solubility

10 mM in DMSO

Smiles

O=C(N[C@@H](CCCCN)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](CO)C(NCC(N[C@@H](CCCNC(N)=N)C(N[C@@H](CC(C)C)C(N[C@@H](CO)C(N1[C@@H](CCC1)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](CCSC)C(N[C@@H]([C@H](O)C)C(N[C@@H](CCC(O)=O)C(N[C@@H](CCC(N)=O)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](CCCCN)N

Molecular Formula

C68H122N20O21S

Molecular Weight

1587.88

References & Citations

[1]Pamela A Lochhead, et al. Activation-loop autophosphorylation is mediated by a novel transitional intermediate form of DYRKs. Cell. 2005 Jun 17;121 (6) :925-36.|[2]Linda E Campbell, et al. Differing substrate specificities of members of the DYRK family of arginine-directed protein kinases. FEBS Lett. 2002 Jan 2;510 (1-2) :31-6.