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SGK1-IN-2

Product Specifications

UNSPSC Description

SGK1-IN-2 (14h) is a selective SGK1 (serum and glucocorticoid regulated kinase 1) inhibitor, with an IC50 of 5 nM at 10 μM ATP concentration[1].

Target Antigen

SGK

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/sgk1-in-2.html

Smiles

O=S(C1=CC(Cl)=CC=C1Cl)(NC2=CC=C(C3=CN=C4C(NN=C4N)=N3)C=C2)=O

Molecular Weight

435.29

References & Citations

[1]Halland N, et al. Discovery of N-[4-(1H-Pyrazolo[3,4-b]pyrazin-6-yl)-phenyl]-sulfonamides as Highly Active and Selective SGK1 Inhibitors. ACS Med Chem Lett. 2014 Oct 23;6(1):73-8.

Shipping Conditions

Room Temperature

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-135893/SGK1-IN-2-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-135893/SGK1-IN-2-SDS-MedChemExpress.pdf

CAS Number

1426214-64-3

Available Sizes

Curated Selection

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