Ebselen derivative 1
Ebselen derivative 1 (Compound 19) is a glutathione peroxidase (GPx) mimic with oral activity. Ebselen derivative 1 demonstrates significant protective effects against cisplatin (HY-17394) -induced hair cell (HC) damage both in vitro and in vivo, effectively reducing oxidative stress, apoptosis, and ferroptosis in hair cells. Ebselen derivative 1 can be utilized in the research of cisplatin (HY-17394) -induced hearing loss [1].
Product Specifications
CAS Number
[3030492-59-9]
UNSPSC
12352005
Target
Apoptosis; Ferroptosis
Type
Reference compound
Related Pathways
Apoptosis
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/ebselen-derivative-1.html
Solubility
10 mM in DMSO
Smiles
O=C1C2=C([Se]N1C3=CC=CN=C3)C(OC)=CC=C2
Molecular Formula
C13H10N2O2Se
Molecular Weight
305.19
References & Citations
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
PDE7B (cAMP-specific 3',5'-cyclic Phosphodiesterase 7B) (MaxLight 550)
TAL1 Mouse Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI6A2]
