(R) -5-Hydroxy-1,7-diphenyl-3-heptanone

(R) -5-Hydroxy-1,7-diphenyl-3-heptanone is a diarylheptanoid that can be found in Alpinia officinarum. (R) -5-Hydroxy-1,7-diphenyl-3-heptanone ameliorates oxidative stress and insulin resistance via activation of Nrf2/ARE pathway[1].

Product Specifications

CAS Number

[100761-20-4]

UNSPSC

12352005

Target

Keap1-Nrf2

Type

Natural Products

Related Pathways

NF-κB

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/r-5-hydroxy-1-7-diphenyl-3-heptanone.html

Purity

99.71

Solubility

DMSO : ≥ 100 mg/mL

Smiles

O=C(C[C@H](O)CCC1=CC=CC=C1)CCC2=CC=CC=C2

Molecular Formula

C19H22O2

Molecular Weight

282.38

References & Citations

[1]Zhang X, et, al. DPHC From Alpinia officinarum Ameliorates Oxidative Stress and Insulin Resistance via Activation of Nrf2/ARE Pathway in db/db Mice and High Glucose-Treated HepG2 Cells. Front Pharmacol. 2022 Jan 17;12:792977.