Human CEACAM-5 / CD66e (499-685) Protein, His Tag (MALS verified)
Human CEACAM-5 (499-685) Protein, His Tag (CE5-H52H8) is expressed from human 293 cells (HEK293) . It contains AA Glu 499 - Ala 685 (Accession # P06731-1) .
Product Specifications
Background
Carcinoembryonic antigen-related cell adhesion molecule 5 (CEACAM5) is also Carcinoembryonic antigen (CEA), Meconium antigen 100, CD antigen CD66e, CEACAM5 belongs to the immunoglobulin superfamily and CEA family. CEACAM5 contains seven Ig-like (immunoglobulin-like) domains. CEACAM5 is homodimer protein which binding of E.coli Dr adhesins leads to dissociation of the homodimer. CEACAM5 is cell surface glycoprotein that plays a role in cell adhesion and in intracellular signaling. CEACAM5 is receptor for E.coli Dr adhesins.
Specifications
This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 21.9 kDa. The protein migrates as 40-55 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Accession Number
P06731-1
Expression Region
Glu 499 - Ala 685
Host
HEK293
Target
CEACAM-5
Conjugation
Unconjugated
Tag
C-10xHis
Source
Human
Stability
● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Endotoxin
1.0 EU per μg
Bioactivity
Immobilized Human CEACAM-5 (499-685) Protein, His Tag (Cat. No. CE5-H52H8) at 1 μg/mL (100 μL/well) can bind Monoclonal Anti-Human CEACAM5 Antibody, Human IgG1 with a linear range of 0.076-1 ng/mL (QC tested).
Format
Powder
Buffer
PBS, pH7.4
Additives
Trehalose
Molecular Weight
21.9 kDa
Shipping Conditions
RT
Storage Conditions
-20°C
Package Size
100ug*1
Product Datasheet
Https://www.acrobiosystems.com/static/main/products/pdf/ds/CE5-H52H8.pdf
Species
Human
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