Mutanolysin

Mutanolysin is a bacteriolytic agent. Mutanolysin is a muralytic enzyme that can prevent hepatic injury. Mutanolysin can digest the cell wall of S. mutans BHT. Mutanolysin reduces TNF-α production in isolated Kupffer cells stimulated with peptidoglycan-polysaccharide. Mutanolysin can prevent elevation of plasma anti-peptidoglycan antibodies and TNF-α levels in rat mode[1][2].

Product Specifications

CAS Number

[55466-22-3]

UNSPSC

12352204

Target

Bacterial; Biochemical Assay Reagents; TNF Receptor

Type

Enzyme

Related Pathways

Anti-infection; Apoptosis; Others

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/mutanolysin.html

Solubility

10 mM in DMSO

Smiles

[Mutanolysin]

References & Citations

[1]Lichtman, S. N., et al., (1992) . Degradation of endogenous bacterial cell wall polymers by the muralytic enzyme mutanolysin prevents hepatobiliary injury in genetically susceptible rats with experimental intestinal bacterial overgrowth. The Journal of clinical investigation, 90 (4), 1313-1322.|[2]Yokogawa, K., et al., (1974) . Mutanolysin, bacteriolytic agent for cariogenic Streptococci: partial purification and properties. Antimicrobial agents and chemotherapy, 6 (2), 156-165.