Mutanolysin
Mutanolysin is a bacteriolytic agent. Mutanolysin is a muralytic enzyme that can prevent hepatic injury. Mutanolysin can digest the cell wall of S. mutans BHT. Mutanolysin reduces TNF-α production in isolated Kupffer cells stimulated with peptidoglycan-polysaccharide. Mutanolysin can prevent elevation of plasma anti-peptidoglycan antibodies and TNF-α levels in rat mode[1][2].
Product Specifications
CAS Number
55466-22-3
UNSPSC
12352204
Target
Bacterial; Biochemical Assay Reagents; TNF Receptor
Type
Enzyme
Related Pathways
Anti-infection; Apoptosis; Others
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/mutanolysin.html
Solubility
10 mM in DMSO
Smiles
[Mutanolysin]
References & Citations
[1]Lichtman, S. N., et al., (1992) . Degradation of endogenous bacterial cell wall polymers by the muralytic enzyme mutanolysin prevents hepatobiliary injury in genetically susceptible rats with experimental intestinal bacterial overgrowth. The Journal of clinical investigation, 90 (4), 1313-1322.|[2]Yokogawa, K., et al., (1974) . Mutanolysin, bacteriolytic agent for cariogenic Streptococci: partial purification and properties. Antimicrobial agents and chemotherapy, 6 (2), 156-165.
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20°C for 2 years
Scientific Category
Enzyme
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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