Abafungin
Abafungin, a antifungal agent, inhibitis the transmethylation at the C-24 position of the sterol side chain, catalyzed by the enzyme sterol-C-24-methyltransferase.
Product Specifications
CAS Number
129639-79-8
Product Name Alternative
BAY-W-6341
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Fungal
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/abafungin.html
Purity
99.10
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
CC1=CC(C)=C(OC2=CC=CC=C2C3=CSC(NC4=NCCCN4)=N3)C=C1
Molecular Formula
C21H22N4OS
Molecular Weight
378.49
Precautions
H302, H315, H319, H335
References & Citations
[1]Borelli C, Schaller M, Niewerth M, et al. Modes of action of the new arylguanidine abafungin beyond interference with ergosterol biosynthesis and in vitro activity against medically important fungi. Chemotherapy. 2008;54 (4) :245-259.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Reference compound1
Clinical Information
Phase 3
Available Sizes
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