TPP-Ce6
Tpp-ce6 is a mitochondria-targeting photosensitizer formed by binding chlorophyll e6 (Ce6) to triphenylphosphine (TPP) via an ester bond. TPP-Ce6 can produce ROS under light irradiation, especially singlet oxygen, which can induce oxidative stress, leading to mitochondrial dysfunction and apoptosis. TPP-Ce6 can be used in the study of mitochondria in apoptosis and energy metabolism as well as cancer therapy[1].
Product Specifications
CAS Number
3030629-73-0
UNSPSC
12352005
Target
Apoptosis; Biochemical Assay Reagents; Reactive Oxygen Species (ROS)
Type
Reference compound
Related Pathways
Apoptosis; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB; Others
Applications
Cancer-programmed cell death
Field of Research
Cancer; Others
Assay Protocol
https://www.medchemexpress.com/tpp-ce6.html
Smiles
Molecular Formula
C94H90N4O6P3
Molecular Weight
1464.66
References & Citations
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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