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Purified Anti-Human CD40 Antibody[3A8]

Product Specifications

Background

CD40 is a type I transmembrane glycoprotein belonging to the TNF receptor superfamily. The mature hCD40 consists of a 172 amino acid (aa) extracellular domain, a 22 aa transmembrane region and a 62 aa cytoplasmic domain . Human and mouse CD40 share 62% aa identity. CD40 is expressed in B cells, follicular dendritic cells, dendritic cells, activated monocytes, macrophages, endothelial cells, vascular smooth muscle cells, and several tumor cell lines.

Abbreviation

CD40

Gene ID

958

UniProt

P25942

Host

Mouse

Reactivity

Human

Immunogen

Recombinant Human CD40 protein

Target

CDW; B-cell surface antigen CD; Tumor necrosis factor receptor superfamily member; TNFRSF; CD40; Bp50; CDW40; TNFRSF5; p50; Tumor necrosis factor receptor superfamily member 5; B-cell surface antigen CD40; CD40L receptor; TNFRSF5; AI326936; B cell associated molecule CD40; B cell surface antigen CD40; B cell-associated molecule; CD 40; CD40 (protein) ; CD40 antigen; CD40 antigen (TNF receptor superfamily member 5) ; CD40 molecule; CD40 protein; CD40 type II isoform; GP39; HIGM1; IGM; IMD3; isoform CRA_a; member 5; MGC9013; Nerve growth factor receptor related B lymphocyte activation molecule; OTTHUMP00000031699; OTTHUMP00000031700; TBAM; T-BAM; TNF receptor superfamily member 5; TNR5; TRAP; Tumor necrosis factor receptor superfamily; Tumor necrosis factor receptor superfamily member 5 precursor

Clonality

Monoclonal

Clone

3A8

Conjugation

Unconjugated

Applications

FCM

Field of Research

Immunology; Cardiovascular; Stem Cells

Purification

>98%, Protein A/G purified

Concentration

≥ 1 mg/mL

Dilution

66

Buffer

Phosphate-buffered solution, pH 7.2, containing 0.05% non-protein stabilizer. Dialyze to completely remove the stabilizer prior to labeling.

Shipping Conditions

Ice bag

Storage Conditions

Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.

Isotype

Mouse IgG2b, κ

Available Sizes

Curated Selection

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