Germicidin B
Germicidin B is an antibiotic with bactericidal properties. Germicidin B can inhibit hexokinase II, with an IC50 of 25.16 μM[1][2].
Product Specifications
CAS Number
[150973-78-7]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Antibiotic; Hexokinase
Type
Natural Products
Related Pathways
Anti-infection; Metabolic Enzyme/Protease
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/germicidin-b.html
Smiles
O=C1OC(C(C)C)=CC(O)=C1CC
Molecular Formula
C10H14O3
Molecular Weight
182.22
Precautions
H302, H315, H319, H335
References & Citations
[1]Lijiang Song, et al. Type III polyketide synthase beta-ketoacyl-ACP starter unit and ethylmalonyl-CoA extender unit selectivity discovered by Streptomyces coelicolor genome mining. J Am Chem Soc. 2006 Nov 22;128 (46) :14754-5.|[2]Yan Bai, et al. Structure-based molecular networking for the target discovery of novel germicidin derivatives from the sponge-associated streptomyces sp. 18A01. J Antibiot (Tokyo) . 2021 Nov;74 (11) :799-806.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Curated Selection
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