Germicidin B

Germicidin B is an antibiotic with bactericidal properties. Germicidin B can inhibit hexokinase II, with an IC50 of 25.16 μM[1][2].

Product Specifications

CAS Number

[150973-78-7]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Antibiotic; Hexokinase

Type

Natural Products

Related Pathways

Anti-infection; Metabolic Enzyme/Protease

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/germicidin-b.html

Smiles

O=C1OC(C(C)C)=CC(O)=C1CC

Molecular Formula

C10H14O3

Molecular Weight

182.22

Precautions

H302, H315, H319, H335

References & Citations

[1]Lijiang Song, et al. Type III polyketide synthase beta-ketoacyl-ACP starter unit and ethylmalonyl-CoA extender unit selectivity discovered by Streptomyces coelicolor genome mining. J Am Chem Soc. 2006 Nov 22;128 (46) :14754-5.|[2]Yan Bai, et al. Structure-based molecular networking for the target discovery of novel germicidin derivatives from the sponge-associated streptomyces sp. 18A01. J Antibiot (Tokyo) . 2021 Nov;74 (11) :799-806.