Germicidin B
Product Specifications
UNSPSC Description
Germicidin B is an antibiotic with bactericidal properties. Germicidin B can inhibit hexokinase II, with an IC50 of 25.16 μM[1][2].
Target Antigen
Antibiotic; Hexokinase
Type
Natural Products
Related Pathways
Anti-infection;Metabolic Enzyme/Protease
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/germicidin-b.html
Smiles
O=C1OC(C(C)C)=CC(O)=C1CC
Molecular Weight
182.22
References & Citations
[1]Lijiang Song, et al. Type III polyketide synthase beta-ketoacyl-ACP starter unit and ethylmalonyl-CoA extender unit selectivity discovered by Streptomyces coelicolor genome mining. J Am Chem Soc. 2006 Nov 22;128(46):14754-5.|[2]Yan Bai, et al. Structure-based molecular networking for the target discovery of novel germicidin derivatives from the sponge-associated streptomyces sp. 18A01. J Antibiot (Tokyo). 2021 Nov;74(11):799-806.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-111331/Germicidin-B-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-111331/
Clinical Information
No Development Reported
CAS Number
150973-78-7
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