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ST3GAL5 Rabbit Polyclonal Antibody

Transfers the sialyl group (N-acetyl-alpha-neuraminyl or NeuAc) from CMP-NeuAc to the non-reducing terminal galactose (Gal) of glycosphingolipids forming gangliosides (important molecules involved in the regulation of multiple cellular processes, including cell proliferation and differentiation, apoptosis, embryogenesis, development, and oncogenesis) . Mainly involved in the biosynthesis of ganglioside GM3 but can also use different glycolipids as substrate acceptors such as D-galactosylceramide (GalCer), asialo-GM2 (GA2) and asialo-GM1 (GA1), although less preferentially than beta-D-Gal- (1->4)-beta-D-Glc- (1<->1)- Cer (LacCer) .

Product Specifications

CAS Number

9007-83-4

Product Name Alternative

3-sialyltransferase CMP-NeuAc:lactosylceramide alpha-2 CMP-NeuAc:lactosylceramide alpha-2,3-sialyltransferase EC 2.4.99.9 Ganglioside GM3 synthase Lactosylceramide alpha-2,3-sialyltransferase Sialyltransferase 9 SIAT9 SIAT9_HUMAN SIATGM3S ST3 beta-galactoside alpha-2,3-sialyltransferase 5 ST3GAL ST3Gal V ST3GAL5 ST3GalV

Abbreviation

ST3GAL5, SIAT9

Swiss Prot

Q9UNP4 Human, O88829 Mouse, Q68G12 Rat

Cellular Locus

Golgi apparatus membrane Curated; Single-pass type II membrane protein

Host

Rabbit

Species Reactivity

Human,Mouse,Rat

Immunogen

Recombinant protein within human ST3GAL5 aa 51-418.

Isotype

IgG

Conjugation

Non-conjugated

Type

Rabbit polyclonal Antibody

Applications

WB

Positive Control

HEK-293 cell lysate, HeLa cell lysate, Jurkat cell lysate, U-87 MG cell lysate, Mouse lung tissue lysate, Mouse skeletal muscle tissue lysate, Rat lung tissue lysate, Rat skeletal muscle tissue lysate.

Concentration

1 mg/mL

Dilution

WB: 1:2,000

Purity

Immunogen affinity purified.

Form

Liquid

Buffer

PBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.1% Sodium Azide.

Molecular Weight

Predicted band size: 48 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.

Recombinant Antibody

No

Frequently Asked Questions

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