Vabicaserin hydrochloride

Vabicaserin hydrochloride is a 5-hydroxytryptamine 2C (5-HT2C) receptor-selective agonist with an EC50 of 8 nM.

Product Specifications

CAS Number

[887258-94-8]

Product Name Alternative

SCA 136

UNSPSC

12352005

Target

5-HT Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/Vabicaserin_hydrochloride.html

Purity

99.47

Solubility

DMSO : 60 mg/mL (ultrasonic; warming; heat to 80°C) |H2O : 4 mg/mL (ultrasonic)

Smiles

[H][C@@]12C3=CC=CC4=C3N(CCNC4)C[C@]1([H])CCC2.Cl

Molecular Formula

C15H21ClN2

Molecular Weight

264.79

References & Citations

[1]Dunlop J, et al. Characterization of Vabicaserin (SCA-136), a selective 5-hydroxytryptamine 2C receptor agonist. J Pharmacol Exp Ther. 2011 Jun;337 (3) :673-80.|[2]Tong Z, et al. Species differences in the formation of Vabicaserin carbamoyl glucuronide. Drug Metab Dispos. 2010 Apr;38 (4) :581-90.