BMS-960 (free base)

BMS-960 free base is a potent and selective S1P1 receptor agonist containing isoxazole, which can be used in the research of immune diseases and vascular diseases[1].

Product Specifications

CAS Number

[1265321-86-5]

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

LPL Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology; Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/bms-960-free-base.html

Solubility

10 mM in DMSO

Smiles

O=C([C@@H]1CN(C[C@@H](O)C2=CC=C(C3=NOC(C4=C(C(F)(F)F)C(C5=CC=CC=C5)=NO4)=N3)C=C2)CCC1)O

Molecular Formula

C26H23F3N4O5

Molecular Weight

528.48

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

References & Citations

[1]Hou X, et al. Regioselective epoxide ring opening for the stereospecific scale-up synthesis of BMS-960, a potent and selective isoxazole-containing S1P1 receptor agonist[J]. Organic Process Research & Development, 2017, 21 (2) : 200-207.