Chitinase, Serratia marcescens

Chitinase, Serratia marcescens (EC 3.2.1.14) has partial lysozyme activity and is widely found in bacteria, fungi, animals and some plants. Chitinase belongs to the glycosyl hydrolase family. Chitinase catalyzes chito-oligosaccharide hydrolysis. Chitinases also can serve as prognostic biomarkers of disease progression. Chitinase can be used in the research of pathogenesis of various human fibrotic and inflammatory disorders, particularly those of the lung (idiopathic pulmonary fibrosis, chronic obstructive pulmonary disease, sarcoidosis, and asthma) and the gastrointestinal tract (inflammatory bowel diseases (IBDs) and colon cancer) [1][2].

Product Specifications

CAS Number

[9001-06-3]

Product Name Alternative

AMCase, Serratia marcescens

UNSPSC

12352204

Hazard Statement

H334

Target

Bacterial

Type

Enzyme

Related Pathways

Anti-infection

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/chitinase-serratia-marcescens.html

Solubility

10 mM in DMSO

Smiles

[Chitinase,serratiamarcescens]

Precautions

P261-P284-P304+P340-P501

References & Citations

[1]Iseli B, et al. Plant chitinases use two different hydrolytic mechanisms. FEBS Lett. 1996 Mar 11;382 (1-2) :186-8.|[2]Mazur M, et al. Chitinases and Chitinase-Like Proteins as Therapeutic Targets in Inflammatory Diseases, with a Special Focus on Inflammatory Bowel Diseases. Int J Mol Sci. 2021 Jun 28;22 (13) :6966.