Estradiol 3-sulfate 17-glucuronide (potassium)

Estradiol 3-sulfate 17-glucuronide potassium is metabolite of estradiol. Estradiol 3-sulfate 17-glucuronide potassium inhibits multidrug resistance protein (MRP) mediated 17β -Estradiol 17- (β -D-Glucuronide) transport with a Ki of 22 μM[1].

Product Specifications

CAS Number

[10392-35-5]

UNSPSC

12352005

Target

P-glycoprotein

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/estradiol-3-sulfate-17-glucuronide-potassium.html

Purity

99.92

Solubility

10 mM in DMSO

Smiles

C[C@@]12[C@](CC[C@@H]2O[C@@H]3O[C@@H]([C@H]([C@@H]([C@H]3O)O)O)C(O[K])=O)([H])[C@@]4([H])[C@@](CC1)([H])C5=CC=C(OS(=O)(O[K])=O)C=C5CC4

Molecular Formula

C24H30K2O11S

Molecular Weight

604.75

References & Citations

[1]Loe DW, et al., ATP-dependent 17 beta-estradiol 17- (beta-D-glucuronide) transport by multidrug resistance protein (MRP) . Inhibition by cholestatic steroids. J Biol Chem. 1996 Apr 19;271 (16) :9683-9.