ST-148 (maleate)
ST-148 maleate is a potent and orally active DENV inhibitor. ST-148 maleate shows antiviral efficacy and low cell toxicity. ST-148 alters the interaction between lipid droplets and the C protein, thereby inhibiting viral replication.[1].
Product Specifications
CAS Number
[390803-40-4]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Dengue Virus; Flavivirus
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/st-148-maleate.html
Purity
99.40
Solubility
DMSO : 58 mg/mL (ultrasonic; warming)
Smiles
O=S(C1=C2C=CC=C(N(C)C)C2=CC=C1)(NCCCCN3CCN(C4=CC=CC=C4OC)CC3)=O.O=C(O)/C=C\C(O)=O
Molecular Formula
C31H40N4O7S
Molecular Weight
612.74
Precautions
H302, H315, H319, H335
References & Citations
[1]Byrd CM, et al. A novel inhibitor of dengue virus replication that targets the capsid protein. Antimicrob Agents Chemother. 2013;57 (1) :15-25.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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